Comparison of the Efficacy of Enrofloxacin and Lactobacillus Plantarum Cell-Free Supernatant Treatments on Vaginitis in Ewes

The aim of the study was to investigate effect different intravaginal treatment strategies on vaginal discharge score, microbiota, bacterial and Enterobacteriaceae counts in nulliparous Merino ewes. All ewes (n=45) received sponges containing 60 mg medroxyprogesterone acetate for 7 days allocated into three equal groups (n=15). Sponges were injected Lactobacillus plantarum cell-free supernatant (SUPER), enrofloxacin (ENRO), or physiologic saline (CON) prior sponge insertion. At removal, 500 IU equine chorionic gonadotropin (eCG) administered all For detection Enterobactericeae counts, samples collected insertion, at withdrawal, 48 h later after withdrawal. Vaginal score not ENRO (2.26±0.18) SUPER (2.20±0.14) compared CON (2.46±0.16). time-dependent alteration significant mean count (P